Our contribution to the XXIII. Meeting of Biochemists and Molecular Biologists
The traditional Czech conference XXIII. Meeting of Biochemists and Molecular Biologists took place from 12th to 13th November 2024 in the Hotel Continental in Brno.
Structural Bioinformatics research group
Research focus and ambitions
Welcome to the website of the Structural Bioinformatics research group. Our research group is affiliated with the National Centre for Biomolecular Research at the Faculty of Science, Masaryk University.
Our research focuses on analysing protein structures, protein fragments, and whole protein families. We visualise, validate, and annotate protein structures, detect protein channels and fragments, and calculate the properties of proteins. In parallel, we also develop cutting-edge software tools for performing these analyses. Our software is integrated into key structural bioinformatics databases such as Protein Data Bank and CATH.
We are looking for new members, students for internships or thesis and postdocs. Research in the field of Structural Bioinformatics is nowadays critical for areas such as drug development and modern diagnostics, join us and participate with us on this challanges.
News
Our Software
Mol*
High-performance graphics and data handling of the Mol* Viewer allows users to simultaneously visualise up to hundreds of (superimposed) protein structures, play molecular dynamics trajectories, and render cell-level models at atomic detail with tens of millions of atoms.
Atomic Charge Calculator II
Atomic Charge Calculator II (ACC II) is an application for fast calculating partial atomic charges. It features 20 empirical methods along with parameters from the literature.
ChannelsDB 2.0
ChannelsDB 2.0 is a comprehensive and regularly updated resource of channels, pores and tunnels found in biomacromolecules deposited in the Protein Data Bank and AlphaFill / AlphaFold databases. As such, it is a unique service for channel-related analyses.
Achievements
Interested in Our Research? Join Us!
If you are a student who wants to gain practical experience, do not hesitate to join us. Look at the available thesis topics. Contact us at radka.svobodova@mail.muni.cz or tomas.racek@ceitec.muni.cz.